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Aiming at the problem that newborn infants need a lot of manpower for real-time nursing, a set of wireless intelligent baby monitoring system is introduced to monitor and warn the physiological activities of infants in nursing state. The system takes STM32f103 microprocessor as the control core, utilizing posture sensor detection, temperature detection, humidity sensor, pulse sensor, wireless communication, display circuit and other peripheral function modules to realize the real-time display and alarm of infant temperature, bed wetting, pulse and other data. Furthermore, the message is transmitted to PC through ZigBee network, and the server function program is designed by using virtual instrument software LabVIEW. The status data can be accessed remotely through Internet, which can effectively monitor the status of infants with high stability. The experiment results show that the system measurement error of the parameters is less than 2.1% and the wireless transmission is stable. The system has laid a good foundation for the design of infant intelligent nursing equipment, and has effective practicability.